Xofluza Side Effects: What They Are and How to Manage Them



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Side Effect(s) Of Irbesartan

Review the side-effects of Irbesartan as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental. If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist. Heart- Chest pain, fast heart beat and edema.

Central Nervous System- Headache, anxiety/nervousness and dizziness.

Gastrointestinal- Diarrhea, stomach upset, heartburn, abdominal pain and nausea/vomiting.

Respiratory- Upper respiratory tract infection, influenza, runny nose and sinus abnormality.

Miscellaneous- Musculoskeletal pain/trauma, fatigue, urinary tract infection and rash.

Other Precautions : *Avoid abrupt withdrawal.

Rexulti Side Effects: What You Should Know

Rexulti (brexpiprazole) is a brand-name oral tablet prescribed to treat certain conditions, such as depression, in adults and some children. As with other drugs, Rexulti can cause side effects, such as weight gain, tiredness, and headache.

Read on to learn about Rexulti's potential common, mild, and serious side effects. For a general overview of Rexulti, including details about its uses, see this article.

These are just a few of the more common side effects reported by people who took Rexulti in clinical trials. These side effects can vary depending on which condition the drug is being used to treat.

More common side effects in people taking Rexulti for depression include:

More common side effects in people taking Rexulti for schizophrenia include:

More common side effects in people taking Rexulti for agitation due to dementia from Alzheimer's disease include:

Mild side effects can occur with Rexulti use. This list doesn't include all possible mild side effects of the drug. For more information, you can refer to Rexulti's prescribing information.

Mild side effects that have been reported with Rexulti include:

These side effects may be temporary, lasting a few days or weeks. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. If you develop a side effect while taking Rexulti and want to tell the FDA about it, visit MedWatch.

Rexulti may cause serious side effects. The list below may not include all possible serious side effects of the drug. For more information, you can refer to Rexulti's prescribing information.

If you develop serious side effects while taking Rexulti, call your doctor right away. If the side effects seem life threatening or you think you're having a medical emergency, immediately call 911 or your local emergency number.

Serious side effects that have been reported and their symptoms include:

  • Neuroleptic malignant syndrome (a possibly life threatening reaction to certain drugs). Symptoms can include:
  • Tardive dyskinesia (unintentional muscle movements). Symptoms can include:
  • excessive blinking
  • trouble controlling movements of your face or tongue
  • waving your arms without meaning to
  • High blood sugar levels. Symptoms can include:
  • feeling unusually thirsty or hungry
  • needing to urinate more frequently than usual
  • weakness
  • tiredness
  • Orthostatic hypotension (a sudden decrease in blood pressure when changing positions). Symptoms can include:
  • dizziness when you stand up after you've been sitting or lying down
  • Seizures (unusual electrical activity in the brain). Symptoms can include:
  • loss of consciousness
  • confusion
  • uncontrollable movements of your arms or legs
  • Trouble swallowing caused by neck spasms (uncontrolled muscle tightening). Symptoms can include:
  • trouble breathing
  • food getting caught in your throat
  • Body temperature regulation problems. Symptoms can include:
  • trouble cooling down after exercise or heat exposure
  • Stroke (decreased or blocked blood flow to the brain), which is more commonly reported in older people using Rexulti. Symptoms can include:
  • confusion
  • numbness or weakness in your arms, face, or legs
  • trouble speaking
  • trouble seeing from one or both of your eyes
  • Increased blood cholesterol or triglyceride levels. This usually doesn't cause noticeable symptoms but would show on blood test results.
  • Severely low white blood cell count, which can increase your risk of infections.
  • Risk of death in certain older adults.*
  • Risk of suicidal thoughts and behaviors in certain children and younger adults.*
  • Weight gain.†
  • Allergic reaction.*‡
  • * Rexulti has a boxed warning for this side effect. This is the most serious warning from the Food and Drug Administration (FDA). To learn more, see the "Side effect specifics" section below.† For more information about this side effect, see "Side effect specifics" below.‡ An allergic reaction is possible after using Rexulti. But this side effect wasn't reported in clinical trials.

    It's possible to experience weight gain as a side effect of Rexulti. This was a common side effect reported in clinical trials of Rexulti, regardless of the condition the drug was used to treat.

    For some people, this weight gain can be serious. Some people in these trials stopped taking Rexulti due to weight gain.

    How much weight you might gain can depend on a variety of factors. These include your dosage of Rexulti, your condition, your diet, your exercise level, and other conditions you have.

    What you can do

    While taking Rexulti, your doctor will closely monitor your weight. They may have you monitor and record your weight at home as well to watch for increases.

    If you're concerned about your weight while taking Rexulti, talk with your doctor or pharmacist. They can recommend ways to maintain a weight that's healthy for you. And if weight gain from Rexulti is bothering you, they can also recommend other treatments for your condition.

    Learn more about some of the side effects that Rexulti may cause.

    Tiredness

    Tiredness is a potential side effect of Rexulti treatment. The drug may cause you to feel tired no matter how much quality sleep you get.

    To see how often tiredness occurred in clinical trials of Rexulti, refer to the drug's prescribing information.

    Note: Insomnia is also a possible side effect of Rexulti. See "Insomnia" below for details.

    What you can do

    Your doctor may recommend that you avoid driving or operating machinery until you know whether taking Rexulti will make you tired.

    Talk with your doctor or pharmacist if you have tiredness that bothers you or concerns you while taking Rexulti. They may suggest ways to help improve your energy levels. They can also suggest that you stop taking Rexulti and try another medication for your condition.

    Headache

    You may have headaches as a side effect of Rexulti. Headaches may go away a few days or weeks after starting Rexulti treatment.

    For details about how often headache occurred in clinical trials, see Rexulti's prescribing information.

    What you can do

    If you're having headaches while taking Rexulti, talk with your doctor or pharmacist. They can try to determine whether there is another potential cause of your headaches. They may also suggest treatments, including an over-the-counter painkiller such as Tylenol (acetaminophen).

    If you have headaches that are severe or do not go away, your doctor may have you stop taking Rexulti and try another medication instead.

    Insomnia

    Although very rare, it's possible to experience insomnia while taking Rexulti. Insomnia refers to problems falling asleep or staying asleep. This side effect wasn't commonly reported by people taking Rexulti in clinical trials.

    What you can do

    Tell your doctor or pharmacist if you're having insomnia while taking Rexulti. They may suggest ways to help with your energy levels during the day. They may also recommend a treatment to help you sleep at night, such as:

  • taking melatonin, an over-the-counter supplement that may help promote sleep
  • improving your sleep hygiene (behaviors and habits that can help with sleep quality)
  • Your doctor may also suggest stopping Rexulti treatment and may have you try a different medication.

    Risk of death in certain older adults

    Rexulti has a boxed warning about the risk of death in certain adults ages 65 years and older. A boxed warning alerts doctors and patients about drug effects that may be dangerous. It's the most serious warning from the Food and Drug Administration (FDA).

    Doctors will typically not prescribe Rexulti to people ages 65 years and older who have psychosis* related to dementia. The only exception is older adults with this condition who take Rexulti for agitation due to dementia from Alzheimer's disease. Rexulti can increase the risk of death in older adults who have dementia-related psychosis.

    * With psychosis, you lose touch with reality and may see or hear things that are not actually there.

    What you can do

    Before you start taking Rexulti, your doctor will review your medical history to make sure Rexulti is a safe, effective treatment for you. If you have concerns about using Rexulti due to this boxed warning, make sure to talk with your doctor.

    Risk of suicidal thoughts and behaviors in certain children and younger adults

    Rexulti has a boxed warning about the risk of suicidal thoughts and behaviors in children and adults ages 24 years and younger. A boxed warning alerts doctors and patients about drug effects that may be dangerous. It's the most serious warning from the Food and Drug Administration (FDA).

    Like other drugs used to treat depression,* Rexulti has been shown to increase the risk of suicidal thoughts and behaviors in children and young adults. This is more likely to occur when you first start taking Rexulti and whenever your dosage is adjusted.

    Keep in mind that depression and other mental health conditions also increase the risk of having suicidal thoughts and behaviors.

    * While Rexulti is not approved to treat depression in children, doctors may prescribe the drug to treat schizophrenia in children ages 13 years and older.

    What you can do

    Before you start taking Rexulti, your doctor will discuss these risks with you. They may also ask if you're comfortable having someone close to you watch for noticeable changes in how you're feeling or acting while taking Rexulti. This could be a friend, family member, or caregiver.

    While you're taking Rexulti, try to be aware of any changes, especially sudden changes, in your behaviors, feelings, moods, or thoughts. Your doctor may recommend stopping Rexulti and trying a different treatment for your condition.

    Allergic reaction

    As with most drugs, Rexulti can cause an allergic reaction in some people. But this side effect wasn't reported in clinical trials.

    Symptoms can be mild or serious and can include:

  • rash
  • itching
  • flushing
  • swelling under your skin, typically in your lips, eyelids, feet, or hands
  • swelling of your mouth, tongue, or throat, which can make it hard to breathe
  • What you can do

    For mild symptoms of an allergic reaction, call your doctor right away. They may recommend ways to ease your symptoms and determine whether you should keep taking Rexulti. But if your symptoms are serious and you think you're having a medical emergency, immediately call 911 or your local emergency number.

    Rexulti may cause several side effects. Here are some frequently asked questions about the drug's side effects and their answers.

    Do the side effects of Rexulti vary by strength?

    Yes, the risk of certain side effects can vary depending on the strength of the drug you're taking. Rexulti tablets are available in the following strengths:

  • 0.25 milligrams (mg)
  • 0.5 mg
  • 1 mg
  • 2 mg
  • 3 mg
  • 4 mg
  • In clinical trials, people taking 3 mg of Rexulti per day reported akathisia (feelings of restlessness and inability to sit still) more often than people taking 2 mg or 1 mg.

    If you'd like to know more about specific side effects of Rexulti that may vary by strength, check out the medication's prescribing information. You can also ask your doctor or pharmacist for more information.

    Can stopping Rexulti treatment cause side effects of withdrawal?

    Yes, it is possible that stopping Rexulti treatment could cause withdrawal. Withdrawal refers to unpleasant effects that can occur when you suddenly stop taking a drug that your body has become dependent on. (With dependence, your body needs a drug to feel as it usually does.)

    Withdrawal wasn't reported in clinical trials of Rexulti. But withdrawal has been reported by people who abruptly stopped taking similar drugs, such as Abilify (aripiprazole). Abilify and Rexulti belong to the same class of drugs called atypical antipsychotics.

    Withdrawal symptoms could include:

  • sleep problems
  • irritability
  • feeling agitated or restless
  • tremors (shaking you cannot control)
  • Due to the risk of withdrawal, do not stop taking Rexulti without first speaking with your doctor. If you want to stop taking Rexulti, your doctor can recommend a plan to help you taper off Rexulti. Tapering off means that your doctor will have you slowly decrease your dosage over time. This is safer than suddenly stopping the drug and can lower your risk of withdrawal.

    If you have concerns about withdrawal effects with Rexulti, make sure to talk with your doctor or pharmacist.

    How long do Rexulti side effects last?

    It depends. Some side effects of Rexulti may be temporary and last a few days or weeks.

    Most mild side effects, such as headache and tremors (shaking you cannot control), should go away on their own. But some other side effects, such as weight gain or akathisia (feelings of restlessness and inability to sit still), may not go away with time.

    If you have side effects that last a long time, bother you, or become severe, be sure to talk with your doctor.

    Keep reading for important precautions you should consider before taking Rexulti.

    Boxed warnings

    This drug has the following boxed warnings, which are serious warnings from the Food and Drug Administration (FDA):

  • risk of death in adults ages 65 years and older who have psychosis related to dementia
  • risk of suicidal thoughts and behaviors in children and adults ages 24 years and younger
  • For details, see the "Side effect specifics" section above.

    Other precautions

    Be sure to talk with your doctor about your health history before you take Rexulti. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. The conditions and factors to consider include:

    Diabetes. Taking Rexulti can cause increases in blood sugar levels. If you have diabetes, Rexulti may cause your blood sugar to rise to dangerous levels. Although rare, this can result in serious complications such as diabetic ketoacidosis, which can be fatal. So if you have diabetes, make sure to talk with your doctor about how to monitor your blood sugar while taking Rexulti.

    Heart problems. Taking Rexulti can cause orthostatic hypotension (a sudden decrease in blood pressure when changing positions). If you have any heart problems, such as heart disease or problems with your heart's electrical pathways, talk with your doctor before taking Rexulti. They can try to determine whether the drug is safe for you to take. If your doctor prescribes Rexulti for your condition, they'll also recommend how to monitor your blood pressure during treatment.

    Compulsive behaviors, including gambling. Taking Rexulti can cause or increase certain urges, including sexual desires and urges to gamble. If you have a history of compulsive behaviors or addiction, talk with your doctor before you start taking Rexulti. This can help them determine whether it's a safe medication for treating your condition.

    Hyperlipidemia. With hyperlipidemia, you have high blood levels of cholesterol or triglycerides. Rexulti can worsen these conditions. Talk with your doctor about whether Rexulti is safe to take, given your lipid levels.

    Kidney problems or liver problems. Your body uses your kidneys and liver to metabolize (break down) and get rid of Rexulti. People with kidney problems or liver damage may need a lower dosage of Rexulti than usual. Your doctor can try to determine whether it's safe for you to use Rexulti for your condition if you have kidney or liver problems.

    Seizure disorders, including epilepsy. Taking Rexulti can increase the risk of seizures (unusual electrical activity in the brain). People with epilepsy or a history of seizures may be at even higher risk. Talk with your doctor about whether Rexulti is safe for you to take if you have epilepsy or a history of seizures.

    Low white blood cell levels. Drugs that are similar to Rexulti can cause low white blood cell levels. It is unknown if Rexulti can also cause this. But to be safe, if you have low levels of white blood cells, you should talk with your doctor before you begin taking Rexulti.

    Allergic reaction. You should not take Rexulti if you've ever had an allergic reaction to the drug or any of its ingredients. Talk with your doctor about which other treatments are better choices for you.

    Alcohol use with Rexulti

    It is unknown whether Rexulti interacts with alcohol.

    If you have liver damage caused by excessive alcohol use (such as alcoholic liver disease or cirrhosis), make sure to talk with your doctor about this. Having liver damage can cause Rexulti to build up in your body, which increases your risk of side effects.

    If you drink alcohol, talk with your doctor about how much alcohol may be safe for you to have while taking Rexulti.

    Pregnancy and breastfeeding while taking Rexulti

    It's not known whether it's safe to take Rexulti while pregnant because no studies have looked at the drug's use during pregnancy. There are some reports of infants exposed to the drug during pregnancy having withdrawal symptoms, however.*

    It's also unknown whether it is safe to take Rexulti while breastfeeding.

    Before taking Rexulti, talk with your doctor if you're pregnant, breastfeeding, or planning to become pregnant or breastfeed.

    * Withdrawal refers to unpleasant effects that can occur when suddenly stopping a drug that your body has become dependent on. And with dependence, the body needs a drug to feel as it usually does. For details, see the "Can stopping Rexulti treatment cause side effects of withdrawal?" in the "FAQ about the side effects of Rexulti" section above.

    Like most drugs, Rexulti can cause mild side effects, including some that are common. Most mild side effects of the drug go away with time and do not require medical attention.

    Serious side effects are also possible. You should talk with your doctor if you experience symptoms of any serious side effects, which are described above in the "Serious side effects of Rexulti" section. You should also talk with your doctor if you become pregnant while taking Rexulti.

    If you'd like to learn more about Rexulti, talk with your doctor or pharmacist. They can answer any questions you have about side effects from taking the drug.

    Besides talking with your doctor, you can do some research on your own. These articles might help:

    Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.


    Side Effects Of Xolair: What You Need To Know

    Xolair (omalizumab) is a prescription drug that's used to treat certain conditions, including asthma. Xolair can cause side effects that range from mild to serious. Examples include injection-related side effects, headache, and fatigue.

    Specifically, Xolair is used to treat:

  • certain types of asthma in adults and in children ages 6 years and older
  • chronic (long lasting) sinus infection with nasal polyps in adults
  • chronic hives from an unknown cause in adults and in children ages 12 years and older
  • The active ingredient in Xolair is omalizumab. (An active ingredient is what makes a drug work.) The drug comes in a few different forms for injection under the skin.

    Keep reading to learn about the common, mild, and serious side effects that Xolair can cause. For a general overview of the drug, including details about its uses, see this article.

    Below are a few of the more common side effects reported by people who took Xolair in studies. These side effects can vary depending on which condition you're receiving the drug to treat.

    More common side effects in people receiving Xolair for asthma include:

  • pain, including joint pain and pain in your legs
  • injection-related side effects*
  • fatigue (low energy)*
  • dizziness
  • itching
  • skin rash
  • More common side effects in people receiving Xolair for chronic (long lasting) sinus infection with nasal polyps include:

  • headache*
  • injection-related side effects*
  • joint pain*
  • abdominal pain
  • dizziness
  • More common side effects in people receiving Xolair for hives include:

    * To learn more about this side effect, see the "Side effects explained" section below.

    Some people may experience mild side effects during Xolair treatment. These side effects may vary depending on the condition you're receiving Xolair to treat.

    Examples of mild side effects that have been reported in people receiving Xolair include:

    * To learn more about this side effect, see the "Side effects explained" section below.

    In most cases, these side effects should be temporary. Some may be easily managed, too. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. You shouldn't stop Xolair treatment unless your doctor recommends it.

    Xolair may cause mild side effects other than the ones listed above. See the Xolair prescribing information for details.

    Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. If you'd like to notify the FDA about a side effect you've had with Xolair, visit MedWatch.

    Xolair may cause serious side effects in some people. Serious side effects that have been reported with Xolair include:

    If you develop serious side effects during Xolair treatment, call your doctor right away. If the side effects seem life threatening or if you think you're having a medical emergency, call 911 or your local emergency number immediately.

    * Xolair has a boxed warning for this side effect. This is the most serious warning from the Food and Drug Administration (FDA). To learn more, see the "Side effects explained" section below.

    Common side effects that have been reported in children receiving Xolair include:

    If you have questions about side effects that your child may experience during Xolair treatment, talk with their doctor.

    Learn more about some of the side effects Xolair may cause.

    Injection-related side effects

    During treatment with Xolair, some people may experience injection-related side effects (also called injection site reactions). These are reactions that can occur where your dose of Xolair is injected. Injection-related side effects were common in studies of Xolair.

    Examples of injection-related side effects include:

  • bruising
  • redness or discoloration
  • burning, stinging, or warmth in the skin
  • itching
  • rash or hives
  • pain
  • swelling
  • What might help

    Injection-related side effects usually happen within 1 hour of an injection and last for fewer than 8 days. Most people who experienced these side effects were less likely to have them with continued use of Xolair. So your risk of this side effect may decrease over time.

    If you experience injection-related side effects during treatment with Xolair, talk with your doctor or pharmacist. They may be able to recommend ways to ease these side effects.

    Hair loss

    Hair loss can occur with Xolair. In studies, this was a rare side effect reported by people receiving Xolair. Hair loss only occurred in people receiving Xolair for hives.

    What might help

    If you experience bothersome hair loss during Xolair treatment, talk with your doctor. They may be able to recommend ways to decrease this side effect. They may also be able to recommend treatment options for hair loss.

    Fatigue

    You may experience fatigue (low energy) during Xolair treatment. This was a common side effect reported by people receiving Xolair for asthma in studies. But fatigue was not reported in studies of people receiving Xolair for hives or chronic (long lasting) sinus infection with nasal polyps.

    What might help

    If you notice a decrease in your energy levels while receiving Xolair, talk with your doctor or pharmacist. They may be able to determine what's causing your fatigue and the best way to treat it.

    Headache

    You may experience headaches when using Xolair. In studies, this was one of the most common side effects reported in people receiving Xolair for chronic (long lasting) sinus infection with nasal polyps or hives. Headaches also commonly occurred in children using Xolair for asthma.

    What might help

    If you experience headaches that are frequent or bothersome to you, talk with your doctor or pharmacist. They may recommend over-the-counter (OTC) treatment options, such as Tylenol (acetaminophen), or they may suggest other ways to treat your headaches.

    Joint pain

    Some people may develop joint pain during treatment with Xolair. Joint pain was a common side effect reported by people receiving Xolair in studies.

    What might help

    If you develop joint pain, talk with your doctor. In some cases, joint pain can be a symptom of a more serious condition called serum sickness. This condition usually causes fever and rash along with joint pain. If you develop serum sickness, your doctor will recommend that you stop Xolair treatment. They can discuss other treatment options for your condition.

    If your joint pain is not associated with serum sickness, your doctor may recommend OTC pain relievers, such as Tylenol. Or they may suggest other ways to decrease your joint pain.

    Allergic reaction, including anaphylaxis

    Like most drugs, Xolair can cause an allergic reaction in some people. In fact, Xolair has a boxed warning for the risk of anaphylaxis,* which is a severe allergic reaction that can be life threatening.

    When you receive your first few doses of Xolair, your doctor will monitor you after your injection. This is done to be sure that you don't develop symptoms of anaphylaxis. Some people who experienced anaphylaxis had reactions after their first dose. But in some cases, anaphylaxis may not occur until a year or more after starting Xolair treatment.

    It's important to understand the symptoms of a mild and serious allergic reaction, including anaphylaxis, so you can get help right away if you develop symptoms.

    Symptoms of a mild allergic reaction can include:

    Symptoms of a more serious allergic reaction, including anaphylaxis, can include:

  • hives
  • constriction (tightening) of the airways in your lungs, which can cause:
  • shortness of breath
  • wheezing or a whistling sound when you inhale
  • coughing
  • pain or tightness in your chest and back
  • fainting
  • swelling under your skin, typically in your eyelids, lips, hands, or feet
  • swelling of your mouth, tongue, or throat, which can make it hard to breathe
  • You should not use Xolair if you have ever had an allergic reaction to Xolair or any of its ingredients, including latex.

    * A boxed warning is the most serious warning from the Food and Drug Administration (FDA). It alerts doctors and patients about drug effects that may be dangerous.

    What might help

    If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. To manage your symptoms, they may suggest:

  • an OTC antihistamine that you swallow, such as Benadryl (diphenhydramine)
  • a product you apply to your skin, such as hydrocortisone cream
  • If your doctor confirms you had a mild allergic reaction to Xolair, they'll decide whether you should continue receiving it.

    If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms could be life threatening and require immediate medical care.

    If your doctor confirms you had a serious allergic reaction to Xolair, they may have you switch to a different treatment.

    Keeping track of side effects

    During your Xolair treatment, consider keeping notes on any side effects you're having. Then, you can share this information with your doctor. This is especially helpful to do when you first start taking new drugs or using a combination of treatments.

    Your side effect notes can include things such as:

  • what dose of the drug you were taking when you had the side effect
  • how soon after starting that dose you had the side effect
  • what your symptoms were from the side effect
  • how it affected your daily activities
  • what other medications you were also taking
  • any other information you feel is important
  • Keeping notes and sharing them with your doctor will help your doctor learn more about how Xolair affects you. Your doctor can use this information to adjust your treatment plan if needed.

    Get answers to some frequently asked questions about Xolair's side effects.

    Does Xolair cause weight gain or weight loss?

    No, you shouldn't experience weight gain or weight loss during Xolair treatment. Changes in weight were not side effects reported by people receiving Xolair in studies.

    If you have unexplained weight changes during treatment with Xolair, talk with your doctor. They can try to determine what may be causing your weight changes.

    Is depression a side effect of Xolair?

    No, Xolair shouldn't cause depression. This was not a side effect reported by people receiving Xolair in studies. But it's possible that living with a chronic (long lasting) condition, such as asthma or hives, can raise your risk of depression.

    If you're feeling depressed during treatment with Xolair, be sure to talk with your doctor right away. They can determine the best way to treat your symptoms of depression.

    Does Xolair cause any long-term side effects?

    Yes, it's possible that Xolair may cause long-term side effects. For example, this medication may raise your risk of heart attack, stroke, or cancer, which can all have long-term complications. But these side effects are rare.

    Short-term, mild side effects are much more common with Xolair than long-term side effects. But if you're concerned about long-term side effects with this drug, talk with your doctor or pharmacist.

    How long do side effects from Xolair typically last?

    It depends on which side effects you're experiencing. For example, injection-related side effects usually go away within 8 days after an injection. These side effects are less likely to happen as your condition is treated with Xolair for a longer period of time.

    Other side effects of Xolair, such as joint pain, may last longer. Some side effects may even last throughout Xolair treatment. If you're concerned about how long a specific side effect could last, talk with your doctor or pharmacist. They may be able to recommend treatment for your side effects.

    Will stopping my Xolair treatment cause any side effects?

    No, you shouldn't experience any side effects if you stop Xolair treatment. But it's possible that stopping Xolair treatment may cause the symptoms of your condition to come back. For example, if you're receiving Xolair to treat asthma, when you stop using the medication, your asthma symptoms may return.

    If you want to stop treatment with Xolair, talk with your doctor first. They may recommend a different medication to treat your condition.

    Before you start treatment with Xolair, talk with your doctor about any other medical conditions you have or other medications you're taking. They can determine whether Xolair may be a safe treatment option for your condition.

    Boxed warning: Anaphylaxis

    Xolair has a boxed warning for the risk of anaphylaxis, which is a severe allergic reaction. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

    If you've had an allergic reaction to any of the ingredients in Xolair, including latex, you should not receive this medication. Symptoms of anaphylaxis may include trouble breathing, swelling of the throat or tongue, and low blood pressure.

    To learn more, see the "Side effects explained" section above.

    Other warnings

    Xolair may not be right for you if you have certain medical conditions or other factors that affect your health. Talk with your doctor about your health history before you use Xolair. The list below includes factors to consider.

    Asthma attack or bronchospasm. If you're experiencing trouble breathing, bronchospasm, or any other symptoms of an asthma attack, you should not use Xolair to treat it. Xolair may not be an effective medication to treat asthma attacks or bronchospasm. If you're experiencing these symptoms, talk with your doctor about the best treatment option for your condition.

    Allergic reaction. If you've had an allergic reaction to Xolair or any of its ingredients, including latex, your doctor likely won't prescribe Xolair. Ask your doctor what other medications are better options for your condition.

    Parasitic infection. If you have a parasitic infection (such as hookworm or roundworm), tell your doctor before you start using Xolair. This drug may raise your risk of a parasitic infection. If you already have this type of infection, Xolair may make your condition worse. Your doctor will likely recommend treating the infection before you start receiving Xolair.

    Cancer. Xolair may increase your risk of cancer. If you have cancer or have had it in the past, tell your doctor before you start Xolair treatment. Your doctor may recommend monitoring you more closely during your Xolair treatment. Or they may recommend a different treatment for your condition.

    Current steroid treatment. If you currently take a steroid medication for asthma or nasal polyps, tell your doctor. They'll recommend that you don't suddenly stop taking the steroid when starting Xolair. Instead, your doctor will have you slowly decrease your dosage until you can safely stop taking the steroid, if needed.

    Alcohol and Xolair

    There are no known interactions between alcohol and Xolair. But drinking alcohol during Xolair treatment could raise your risk of certain side effects. For example, both alcohol and Xolair may cause a headache or nausea. So drinking alcohol with Xolair may make these side effects worse.

    If you drink alcohol, talk with your doctor about how much (if any) may be safe for you to drink during treatment with Xolair.

    Pregnancy and breastfeeding while receiving Xolair

    It's not known whether Xolair is safe to use during pregnancy or while breastfeeding.

    If you're pregnant or breastfeeding, or planning to become pregnant or to breastfeed, talk with your doctor before starting Xolair treatment.

    You may experience side effects during treatment with Xolair. But most side effects are mild. Before starting Xolair treatment, talk with your doctor about your risk of side effects with this drug.

    Questions that you may want to ask include:

  • Do I have a higher risk of side effects due to my medical conditions?
  • How should I treat side effects that I experience?
  • What should I do if I become pregnant during treatment with Xolair?
  • To learn more about Xolair, see these articles:

    To get information on different conditions and tips for improving your health, subscribe to any of Healthline's newsletters. You may also want to check out the online communities at Bezzy. It's a place where people with certain conditions can find support and connect with others.

    Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.






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